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These data suggested that dietary L-carnitine supplementation tended to increase protein degradation by inhibiting protein synthesis in the fasting state

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Kinase assays for pseudo-substrate characterisation Fifty nanomolar CDK11 p58 -cyclin L (1319)-SAP30BP complex (WT or mutant) was incubated with 6 M GST-SF3B1 1463 and 2 mM ATP in a total volume of 100 L, in assay buffer (150 mM NaCl, 25 mM HEPES-KOH pH 7.9, 9 mM MgCl 2 , 2 mM DTT, 2.5% (v/v) glycerol) for 60 min at RT

Epitalon activates telomerase gene expression, triggering a cascade of cellular responses